I had the pleasure of going to the 2010 Game Development Conf at the Moscone Center in SF. This year's conference had the highest attendence in year's. With that being said the Moscone Center was very helpful; as someone who use a wheelchair attending a conference of this size can be daunting but the people at the Moscone Center made sure I had everything I needed from good parking to an accessible bathroom!
This conference was truly amazing I met with a lot of amazing people learned lot, saw a lot of great stuff and had a blast.